This rune is a relic of the Legacy Chain. When an unsuspecting villain crosses one, it self destructs and drains 50 endurance from everyone nearby. The rune is also targetable and has the same Hit Points as a Minion of the same level. Apparently, if the rune is attacked and its life bar drops to 50% the rune will self destruct.
The Uruz Runes are found:
- In the the Find info on coral key mission from Operative Renault, on the Operative Renault Strike Force.
These strange runes glow ominously with unstable mystic energy.